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testagen

In the wider archive
formula -
Bioregulator
Khavinson VKh · St. Petersburg Institute of Bioregulation and Gerontology · 2003
testagen·Bioregulator·formula ,
What the corpus says

Polypeptide fraction from bovine testicular tissue, used in Russian andrology for low sperm count and age-related androgen decline. Earlier attribution to a defined KEDW tetrapeptide has been retracted in our dossier; this is a tissue extract, not a sequence.

mechanism confidence: low

PubMed papers
0
in our PubMed map
Russian full-text sources
15
Russian full-text PDFs
Archive notes
5
from archive synthesis
Confidence
low
archive rating
Research synthesis
Mechanism

Polypeptide fraction from bovine testes (not a defined sequence). The mechanism is inferred from the source organ: testosterone-like regenerative + tissue-specific effects on testicular function. Direct studies are sparse. most adjacent literature covers male reproductive biology (sperm cryopreservation, oligospermia, androgen anabolic steroid misuse). The compound sits in the methodological shadow of prostatilen (prostate extract). same Cytomed production paradigm but less studied. Note: registry entry incorrectly attributes testagen to KEDW tetrapeptide. this is wrong; KEDW is pancragen. Testagen is a polypeptide fraction (testicular extract), not a defined tetrapeptide.

Key findings
  1. Adjacent: oxidative stress model in vitro. polypeptides from testes show biological activity (Khochenkova 2022). note: not the registered testagen product, similar polypeptide class
  2. Adjacent: sperm DNA fragmentation, oligospermia, FT-IR spectroscopy methods (Nechiporenko 2024)
  3. Adjacent: lactational physiology and pathology. context for reproductive peptide use (Budanov 2019)
  4. Adjacent: pre-gravidar preparation for couples with recurrent bacterial vaginosis. peptide combinations used (Tapilskaya 2018)
  5. No DIRECT primary literature on registered Testagen® product found in CyberLeninka search
Evidence quality

grade: Low. Testagen as a registered product has minimal direct study. Most "testagen" papers are about testicular biology, male infertility, or adjacent peptides. The compound deserves more dedicated pharmacology.

Open questions
  • What is the active principle in testagen? Polypeptide fraction composition has not been worked out
  • Is testagen different from generic testicular extracts?
  • Registry error: KEDW was attributed to testagen. this is wrong (pancragen is KEDW)
  • Any modern pharmacological study in male reproductive medicine?

6 Russian sources synthesised · confidence: low

Russian full-text papers (CyberLeninka) · 15

Open-access Russian academic PDFs linked where we have them.

cyberleninka_00.pdfcyberleninka_01.pdfcyberleninka_02.pdfcyberleninka_03.pdfcyberleninka_04.pdfcyberleninka_05.pdfcyberleninka_06.pdfcyberleninka_07.pdfcyberleninka_08.pdfcyberleninka_09.pdfcyberleninka_10.pdfcyberleninka_11.pdfcyberleninka_12.pdfcyberleninka_13.pdfcyberleninka_14.pdf
Papers indexed on PubMed

no PubMed-indexed literature in the corpus.

Reviewed against the archive corpora on 2026-09-16. Source-grounded. No clinical claims. Synthesis prose may preserve published experimental context from papers; that is research history, not a recommendation.

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