What the corpus says
Normoftal bioregulator peptide (Khavinson school). Limited primary literature; full source PDFs preserved in the dossier.
mechanism confidence: low
PubMed papers
0
in our PubMed map
Russian full-text sources
23
Russian full-text PDFs
Archive notes
4
from archive synthesis
Confidence
low
archive rating
Research synthesis
Mechanism
Synthetic peptide for retinal disease. Mechanism: tissue-specific retinal bioregulation. but the dedicated direct literature is sparse. Most adjacent literature covers:
- oxidative resistance of atherogenic lipoproteins in elderly hypertensive patients
- membrane-tropic homeostatic tissue-specific bioregulators (Yamskova-Krasnov-Rybakova-Bogdanov-Ilina 2013). a broader class of endogenous bioregulators from mammalian tissues that includes peptide + protein modulators
- experimental diabetes retinal histology (Wistar rats, streptozotocin 50 mg/kg i.p., glucose >300 mmol/L, retinal pericyte ghost cells 3× elevated)
- neuronal markers in primary open-angle glaucoma (Gabdrakhmanova 2018). same paper as retinalamin
- AMD treatment with peptide bioregulator complex (Derkach-Trofimova 2021, Khavinson school).
Key findings
- Adjacent: AMD treatment with peptide bioregulator complex. combination peptide therapy for AMD (Derkach-Trofimova 2021, Khavinson school)
- Adjacent: streptozotocin-diabetic rat retinal histology. baseline for retinal bioregulator studies (Kresyun 2014)
- Adjacent: neuronal markers in glaucoma tear fluid (Gabdrakhmanova 2018)
- Adjacent: homeostatic tissue-specific bioregulators. broader class characterisation (Yamskova 2013)
Evidence quality
grade: Low. Normoftal-specific literature is sparse. Most direct findings are from retinalamin studies which overlap in mechanism.
Open questions
- Is normoftal structurally distinct from retinalamin?
- Comparative head-to-head with retinalamin in AMD/glaucoma?
- Independent confirmation of efficacy beyond Khavinson school
Russian full-text papers (CyberLeninka) · 23
cyberleninka_00.pdfcyberleninka_01.pdfcyberleninka_02.pdfcyberleninka_03.pdfcyberleninka_04.pdfcyberleninka_05.pdfcyberleninka_06.pdfcyberleninka_07.pdfcyberleninka_08.pdfcyberleninka_09.pdfcyberleninka_10.pdfcyberleninka_11.pdfcyberleninka_12.pdfcyberleninka_13.pdfcyberleninka_14.pdfcyberleninka_15.pdfcyberleninka_16.pdfcyberleninka_17.pdfcyberleninka_18.pdfcyberleninka_19.pdfcyberleninka_20.pdfcyberleninka_21.pdfcyberleninka_22.pdf
Papers indexed on PubMed
no PubMed-indexed literature in the corpus.
Reviewed against the archive corpora on 2026-09-16. Source-grounded. No clinical claims. Synthesis prose may preserve published experimental context from papers; that is research history, not a recommendation.